Latest News
Learn about what we have been working on, find out what we are interested in, and see our accomplishments!
I recently attended a Gordon Research Seminar and Conference on Extracellular Vesicles in Newry, Maine. In the Blackburn lab one focus of my project is based on how pediatric tumor neural stem cells communicate with each other. Extracellular Vesicles (EVs) caught my attention when I attended a research symposium on EVs at the University of…
This summer (May 2022) I had a chance to visit the neighboring Cincinnati to attend the 13th International Workshop on Myeloid Stem Cells and Leukemia.. Coming from a Myeloid Leukemia and underlying transcription control background, my main goal to attend this meeting was to update myself about the field and to try and apply current…
I was very fortunate to be invited to give a Mini-symposium podium presentation at the AACR 2022 Annual Meeting in New Orleans, LA on April 10, 2022. I was able to attend this meeting in part by being awarded a GMaP Region 1 North Travel Award which is funded by the NCI, and the Office…
A major goal of our lab’s PRL-3 projects is to find a way to inhibit PRL-3 activity. PRL-3 is essential for the growth and spread of many types of cancer, so if we can find a way to block PRL-3, we could potentially impact many patients. However, the drugs used to target PRL-3 are still…
Meghan and Henry have starred in a JoVE (Journal of Visualized Experiments) video article explaining how the lab transplants human cancer cells into zebrafish and uses them for high-throughput drug screening. The benefit of this xenograft model is that we can rapidly screen though hundreds of compounds in living animals, which allows us to find…
The lab’s first research manuscript is out! Min’s research defined the oncogenic role of PRL-3 phosphatase in T-cell acute lymphoblastic leukemia (T-ALL), which is a very progressive pediatric cancer and lacks targeted therapies. Our findings show that PRL-3 promotes T-ALL development/onset in zebrafish models and plays a role in engraftment in mouse xenograft models. Cell-culture…