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(859) 323-9770 jsblackburn@uky.edu

Latest News

Learn about what we have been working on, find out what we are interested in, and see our accomplishments!

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I had a great time in Jessi’s lab this summer! I was able to learn a variety of techniques and protocols through all of the amazing people there! One such technique was embryo injections into the eggs of zebrafish. I…

    Our lab studies the human prenylated protein tyrosine phosphatase PRL3 and its role in promoting metastatic activity in cancer. My project is more specifically focused on the mechanisms of PRL3 regulation. The current work is focused on how…

At our last lab meeting, I updated everyone on my project that has thus far focused on designing nanobodies, derived from alpaca heavy-chain only antibodies, that specifically bind to PRL-3. One of the biggest caveats to studying PRL-3 is the…

Recent Publications

Read our most recent papers.

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Meghan and Henry have starred in a JoVE (Journal of Visualized Experiments) video article explaining how the lab transplants human cancer cells into zebrafish and uses them for high-throughput drug screening. The benefit of this xenograft model is that we…

The lab’s first research manuscript is out! Min’s research defined the oncogenic role of PRL-3 phosphatase in T-cell acute lymphoblastic leukemia (T-ALL), which is a very progressive pediatric cancer and lacks targeted therapies. Our findings show that PRL-3 promotes T-ALL…

The first research paper from the lab has been published! This project was done by our high schooler (who is now killing it at Harvard) Shea Hausman, in collaboration with Chunming Liu’s and Dave Watt’s groups at UK. They made…

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