I recently attended a Gordon Research Seminar and Conference on Extracellular Vesicles in Newry, Maine. In the Blackburn lab one focus of my project is based on how pediatric tumor neural stem cells communicate with each other. Extracellular Vesicles (EVs)…
This summer (May 2022) I had a chance to visit the neighboring Cincinnati to attend the 13th International Workshop on Myeloid Stem Cells and Leukemia.. Coming from a Myeloid Leukemia and underlying transcription control background, my main goal to attend…
I was very fortunate to be invited to give a Mini-symposium podium presentation at the AACR 2022 Annual Meeting in New Orleans, LA on April 10, 2022. I was able to attend this meeting in part by being awarded a…
My name is John Blair, I am a senior at Paul Laurence Dunbar High School and the Math Science Technology Center in Lexington, KY. This school year, I conducted research at the University of Kentucky. During my time at the…
I had a great time in Jessi’s lab this summer! I was able to learn a variety of techniques and protocols through all of the amazing people there! One such technique was embryo injections into the eggs of zebrafish. I…
Our lab studies the human prenylated protein tyrosine phosphatase PRL3 and its role in promoting metastatic activity in cancer. My project is more specifically focused on the mechanisms of PRL3 regulation. The current work is focused on how…
At our last lab meeting, I updated everyone on my project that has thus far focused on designing nanobodies, derived from alpaca heavy-chain only antibodies, that specifically bind to PRL-3. One of the biggest caveats to studying PRL-3 is the…
A major goal of our lab's PRL-3 projects is to find a way to inhibit PRL-3 activity. PRL-3 is essential for the growth and spread of many types of cancer, so if we can find a way to block PRL-3,…
Meghan and Henry have starred in a JoVE (Journal of Visualized Experiments) video article explaining how the lab transplants human cancer cells into zebrafish and uses them for high-throughput drug screening. The benefit of this xenograft model is that we…
Hello everyone! So something cool that Meghan and I were recently tasked with was starring in a movie! By publishing through JOVE, we were filmed performing the different methods and procedures we used to xenograft primary patient samples into zebrafish…