Caroline’s PRL-3 nanbody project was featured in UKnow!
LEXINGTON, Ky. (Aug. 10, 2023) – Using antibodies derived from alpacas, a University of Kentucky research team has developed a tool that could lead to new therapies to stop the growth of several types of cancer. While cancer researchers have known…
Ella’s summer wrap-up!
This summer I worked under Evelyn as a research assistant where we investigated different, non-traditional drugs as radiosensitizers for DIPG tumors. I did this through culturing SCC127 cells and injecting them into zebrafish embryos and testing these drugs both…
Joanne’s summer in the lab
This week I just wrapped up presenting my summer project with Majd on the potential mechanism involving mitochondrial alterations in Amiloride’s targeting of leukemia-initiating cells (LICs) of T-cell lymphoblastic leukemia (T-ALL) through NHE1 inhibition. I was able to look…
Majd passed her qual!
This summer marked an important moment in my academic journey as I successfully passed my PhD qualifying exam and I am now a Pharmacology PhD candidate! It has been an incredible experience filled with growth, learning and support from…
Development of PRL-3 Specific Nanobodies, PLOS One (2023)
Phosphatase of Regenerating Liver-3 (PRL-3) is associated with the progression and spread of cancer, but the limited number of research tools available to study this protein have prevented us from fully understanding of PRL-3's role in cancer. To address…