I worked with Dr. Blackburn this summer through the Markey STRONG program. My project’s scope focused primarily on the radioresistance associated with missense mutations in TP53, and how those mutations (uniquely) collaborate with the H3K27M mutation found in 80% of…
This summer, I had the opportunity to work in the Blackburn Lab through the Kentucky INBRE Summer Research Program. I investigated Deferoxamine as a drug therapy to prevent relapse in patients with T-cell Acute Lymphoblastic Leukemia. It was an invaluable…
In October 2023 me and Jessi had the chance to go to Durham-North Carolina to attend the 16th Zebrafish Disease Models Society annual meeting. This meeting brings together researchers using zebrafish to model different human diseases. Research findings from the…
The Wnt/β-catenin pathway is important in cancer and stem cell biology, making it a potential target for therapy. However, using Wnt inhibitors in the clinic is difficult due to off-target effects and interactions with other pathways. In this study, we…
Immunofluorescent microscopy allows us to see where proteins are located and how much of them are present in cells. The location of a protein in a cell can affect its function because certain interactions happen in specific areas. This article…
Phosphatase of regenerating liver 3 (PRL-3) is linked to cancer metastasis and interacts with the cyclin and CBS domain divalent metal cation transport mediator (CNNM) family of proteins to manage the levels of magnesium and other metals within cells. Despite…
