Ty’s going to med school!
Beyond my undergraduate coursework, research has been the most educational and rewarding experience I have participated in. The Blackburn Laboratory fostered the supportive environment I needed to reach my goals, and allowed me to take my education to the next…
Targeting mitochondria to stop leukemia stem cell self-renewal. Cancer Biology & Therapy (2025)
In T-cell acute lymphoblastic leukemia (T-ALL), a rare but aggressive childhood cancer, some leukemia cells—called leukemia stem cells (LSCs)—can evade chemotherapy and cause relapse. Majd’s review explores an exciting new approach: targeting mitochondria, the powerhouses of cells, to eliminate these…
The PACT Network: PRL, ARL, CNNM, and TRPM Proteins in Magnesium Transport and Disease, International Journal of Molecular Sciences (2025)
Magnesium is essential for many cellular functions, and its balance is tightly controlled to prevent disease. Trace's review highlights an emerging network of proteins—PRL, ARL, CNNM, and TRPM (collectively termed PACT)—that work together to regulate magnesium levels. By understanding how…
Targeting Leukemia Stem Cells in T-ALL with Amiloride
Despite advancements in treatment, T-cell acute lymphoblastic leukemia (T-ALL) remains difficult to cure when it relapses, largely due to leukemia stem cells (LSCs), a small but powerful group of cells that resist therapy and restart the disease. Using a zebrafish…
