Ella’s summer wrap-up!
This summer I worked under Evelyn as a research assistant where we investigated different, non-traditional drugs as radiosensitizers for DIPG tumors. I did this through culturing SCC127 cells and injecting them into zebrafish embryos and testing these drugs both…
Joanne’s summer in the lab
This week I just wrapped up presenting my summer project with Majd on the potential mechanism involving mitochondrial alterations in Amiloride’s targeting of leukemia-initiating cells (LICs) of T-cell lymphoblastic leukemia (T-ALL) through NHE1 inhibition. I was able to look…
Majd passed her qual!
This summer marked an important moment in my academic journey as I successfully passed my PhD qualifying exam and I am now a Pharmacology PhD candidate! It has been an incredible experience filled with growth, learning and support from…
Development of PRL-3 Specific Nanobodies, PLOS One (2023)
Phosphatase of Regenerating Liver-3 (PRL-3) is associated with the progression and spread of cancer, but the limited number of research tools available to study this protein have prevented us from fully understanding of PRL-3's role in cancer. To address…
Mid-summer update from Chase
These gifs show the early development of zebrafish embryos after being injected with morpholino oligonucleotides (MO) which target and disrupt the function of their respective target genes. The exploding embryos were injected with MO targeting PRL-1, 2a, 2b, and…
Lab superstars for June 2023!
Thanks to our June 2023 superstars for making the lab awesome! Izzy Snyder: One last lab superstar award for Izzy for her general amazingness and for getting everything and everyone organized before she left for her new job as a…
Review on Zebrafish as Avatar Models, International Journal of Molecular Sciences (2023)
The increasing number of anti-cancer drugs poses a challenge for doctors who need to choose the best treatment for patients. Precision cancer medicine aims to match a drug with a tumors unique characteristics to maximize its effectiveness. However, current approaches…